Androgen receptor and 5α-reductase immunohistochemical profiles in extramammary Paget disease
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منابع مشابه
Extramammary Paget Disease: Minimal Surgical Therapy
BACKGROUND Extramammary Paget disease (EMPD) is an uncommon malignant neoplasm affecting apocrine gland-bearing skin which usually occurs in the anogenital area of patients older than 50 years. Although Mohs micrographic surgery (MMS) is recommended for the treatment of EMPD, wide local excision has also been performed by many other surgeons including dermatosurgeons. However, the extent of an ...
متن کاملExtramammary Paget disease of the vulva: immunohistochemical analysis of neoangiogenesis and epithelial-mesenchymal transition markers expression.
BACKGROUND Extra-mammary Paget's disease of the vulva (EMPDV) is an infrequent chronic disease that often recurs. The aim of the study was to assess the presence of neoangiogenesis and the expression of epithelial-mesenchymal transition (EMT) markers in EMPDV, and their potential correlation with stromal invasion. METHODS All the women consecutively treated for EMPDV at our Institute, between...
متن کامل[Extramammary Paget disease treated with 5% imiquimod cream].
observed in scalp discoid lupus erythematosus. Arch Dermatol. 2009;145:1406--9. 4. Uysal AC, Alagöz MS, Unlü RE, Sensöz O. Hairdresser’s syndrome: a case report of an interdigital pilonidal sinus and review of the literature. Dermatol Surg. 2003;29:288--90. 5. Morrell JF. ‘‘Pilonidal’’ sinus of the sole. Arch Dermatol. 1957;75:269. 6. Sakai R, Higashi K, Otha M, Sugimoto Y, Ikoma Y, Horiguchi Y...
متن کاملExtramammary Paget disease: a report of 10 cases.
Extramammary Paget disease (EMPD) is a very rare form of intraepithelial adenocarcinoma. We report the cases of EMPD diagnosed in a referral hospital over a 5-year period from 2009 to 2013. Ten cases of EMPD were diagnosed in 4 men and 6 women aged between 50 and 79 years. Erroneous clinical diagnoses led to diagnostic delays of 1 to 5 years in all cases. Six patients had in situ lesions and de...
متن کاملExtramammary Paget Disease of the Vulva - Case Report.
Extramammary Paget disease (EPD) is a rare malign neoplasm that may affect the vulva and has manifestations common to benign diseases such as itching, pain and eczema. This leads to delay in diagnosis and consequent worse prognosis. The definitive diagnosis is obtained by biopsy of the vulva, which shows Paget cells. The treatment of choice is wide excision with margins, which leads to sequelae...
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ژورنال
عنوان ژورنال: British Journal of Dermatology
سال: 2009
ISSN: 0007-0963
DOI: 10.1111/j.1365-2133.2009.09603.x